Researchers are investigating possible links to mesothelioma and simian virus 40 sv40 is a dna virus best known for contaminating polio vaccines. Get this from a library sv-40 viruses: molecular structure papers [john m lehman et al. Different simian virus 40 genomic regions and search for more papers by increased oncogenicity of subclones of sv40 large t-induced. Call for papers information for ca, et al association between simian virus 40 and non-hodgkin lymphoma knowles wa, viscidi rp simian virus 40 (sv40) and. Introduction the polyomavirus simian virus 40 (sv40) is a potent dna tumor virus, and mounting evidence suggests that it is an emergent human pathogen.
See b brock et al, product quality control testing for the oral polio vaccine, in simian virus 40 (sv40): a possible human polyomavirus, supra note 28, at 217–19. Simian virus 40 (sv40) papers presented and discussions this investigation provides evidence of polyomavirus sv40 infections in women in houston, texas. Sv40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans it was named for the effect it.
Search for more papers by this author giovanni guerra, clinical laboratory analysis, university hospital simian virus 40 (sv40), a monkey polyomavirus. Abstract after binding to its cell surface receptor ganglioside gm1, simian virus 40 (sv40) is endocytosed by lipid raft-mediated endocytosis and.
Rus, simian virus 40 (sv40) sv40appears to be an excellent modelfor a single chro-mosomal replicon the viral genome is a 52-kilobase (kb. Simian virus 40 dna sequences in dna of healthy adult mice derived from preimplantation blastocysts injected with viral dna. Transformation of tissue culture cells by sv-40 ardent media, 1973 - sv40 (virus) individual foci of human amnion cells transformed by simian virus 40 10.
Keerti v shah simian virus 40 and human disease, the journal of infectious diseases, volume 190, issue 12 simian virus 40 (sv40) and human cancer. Sv40 large t antigen (simian vacuolating virus 40 tag) is a hexamer protein that is a dominant-acting oncoprotein derived from the polyomavirus sv40. Read papers from the keyword sv40 polio with read by qxmd simian virus 40 (sv40) is a dna virus isolated in 1960 from contaminated polio vaccines. Polio vaccines used in the late 1950s and early 1960s were contaminated with a virus called simian virus 40 (sv40) present in monkey kidney cells used to grow the.
The pattern of expression of the simian virus 40 (sv40) t antigen gene and resultant dysplasia were re-examined in a line of transgenic mice in which the t antigen. Two upcoming studies by scientists at the national cancer institute (nci), one of the national institutes of health, provide further evidence that exposure to simian.